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I wrote most of the question before finding myself not certain of whether it was actually a good fit for the site. I think it's a viable question overall as to how one should best defend when your reflexes and coordination are a bit off. What leaves me a bit iffy is that I'm having trouble finding a way of expressing it that isn't "what's the best way?" (opinion) or "has this been covered in martial arts?" (lists).

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I think the question is fine. Here is one attempt at wording:

How should I modify my self-defense strategy if I know I am impaired?

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